- Neurological Signs
- Bone remodelling is an active and dynamic process that relies on the correct balance between bone resorption by osteoclasts and bone deposition by osteoblasts.
- The remodeling cycle consists of three consecutive phases: resorption, during which osteoclasts digest old bone; reversal, when mononuclear cells appear on the bone surface; and formation, when osteoblasts lay down new bone until the resorbed bone is completely replaced.
- Enthesophyte formation is new bone at the site of attachment of a tendon, ligament, or joint capsule to bone.
- Osteoporosis defines a group of skeletal disorders that are characterized by loss of bone mass (osteopenia) with the remaining bone appearing normal.
- There is P3 osteopenia and remodeling of the distal aspect of P3.
- Pathogenesis: Osteoporosis results from bone resorption exceeding bone formation.
- Note: When inadequate bone mineralization is microscopically evident, the disease should not be called osteoporosis.
- Causes: Disuse osteoporosis is caused by lack of physical exercise, reduction in weight bearing and immobilization of the limbs. Osteoporosis of senility may be partially due to reduced physical activity. Malnutrition, hyperadrenocorticism, prolonged use of corticosteroids, thyrotoxicosis, hyperparathyroidism and other hormone imbalances also can cause osteoporosis.
- subchondral sclerosis?
- A sclerotic lesion is an unusual hardening or thickening of your bone.
- Remodeling imbalance owing to failure of the resorptive process can result in dense (sclerotic) bones. Bone sclerosis is defined as “an abnormal increase in density and hardening of bone”
- Ankylosis is a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint, which may be the result of injury or disease.
- subchondral erosions
- The formation of large “holes” in the body of the navicular bone itself, believed to be enlarged vascular channels