• Copper deficiency can develop in ruminants fed forage grown in copper-deficient soil. Copper is necessary for the metabolism of iron. Copper deficiency may occur secondary to high dietary molybdenum or sulfate in cattle and can develop in pigs fed whey diets. Low blood copper concentrations or low copper concentrations in liver biopsies (more definitive) are diagnostic. Treatment is oral or injectable copper supplementation.
  • Oral or injectable iron supplementation is indicated as treatment for iron deficiency; any source of blood loss must be eliminated.
  • B vitamin deficiencies are rare. Certain drugs (anticonvulsants, drugs that interfere with folate metabolism) have been associated with development of folate or cobalamin deficiency, leading to a normocytic, normochromic, nonregenerative anemia.